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Coronary artery bypass grafting

New plumbing around blocked coronaries: conduit from the chest wall and leg, grafted onto the arteries beyond their disease, classically on a heart stopped and lent to a machine.

Indication: Left main or three-vessel coronary disease, and diabetics with multivessel disease, where surgery outlives stenting.

Part of Cardiac Surgery4 stages4 complications to knowopen
Cardiac surgery in progress: the team around an open chest
Pfree2014 · CC BY-SA 4.0

Read the imaging first

Angiography
Coronary angiogram of the left coronary system, the arteries drawn in dark contrast against a grey field, with a tight narrowing in the proximal left anterior descending artery
Coronary angiography · a preocclusive stenosis in the proximal LAD after thrombus aspiration

Practice before you scrub

Read the coronary angiogram

A 68-year-old with diabetes and exertional angina despite medical therapy. Coronary angiography is performed. (Fictional educational case.)

  • Proximal LAD and left main disease pull hardest toward CABG: the muscle at stake is the argument.
  • A lesion is only bypassable if the vessel beyond it is worth sewing to: the surgeon reads targets, not just narrowings.

The anatomy the operation is built on

Educational illustration
Anterior view of the heart with the coronary arteries drawn and labelled
Coronary anatomy · anterior view with the left main, LAD, circumflex and right coronary arteries
Educational illustration
Diagram of the heart and its coronary arteries as seen from the left anterior oblique angle
Angiographic projection · left anterior oblique view of the heart and coronaries
Educational illustration
Diagram of the heart and its coronary arteries as seen from the right anterior oblique angle
Angiographic projection · right anterior oblique view of the heart and coronaries
Educational illustration
Gray's Anatomy plate of the anterior chest wall showing the internal mammary artery and its branches
Conduit anatomy · the internal mammary (thoracic) artery and its branches, Gray's Anatomy plate 522
Educational illustration
Medical illustration of a heart after triple coronary artery bypass grafting, showing the grafted vessels
CABG · a triple bypass illustrated: grafts routed around the diseased segments to the vessels beyond them
Educational illustration
Medical illustration of one typical way a heart-lung machine is connected to the veins and arteries near the heart
Cardiopulmonary bypass · one typical way the circuit is connected to the great vessels
Educational illustration
Three-panel medical illustration: the catheter route from the groin to the heart, the coronary arteries on the heart, and the angiographic view with a narrowing circled
Coronary angiography, illustrated · catheter route, coronary tree, and the angiographic view of a stenosis

On the tray for this operation

Test yourself on the tray

Stage

1 / 4

Sternotomy and conduit harvest

Median sternotomy; the left internal mammary artery is taken down from the chest wall while the saphenous vein is harvested from the leg.

Watch for: Sternal malunion or deep sternal wound infection · Conduit injury during harvest

Why are we operating?

CABG re-plumbs the heart's own blood supply: conduits carry blood past blocked coronaries so whole territories are revascularised at once. It is considered when disease is too proximal, too diffuse or too important for stents, classically left main disease, proximal LAD disease, multivessel disease, and the diabetic patient with several territories at risk.

Pulls toward surgery

Left main diseaseProximal LAD diseaseMultivessel diseaseDiabetes with multivessel diseaseSymptoms despite medical therapyFailed or unsuitable PCIIschaemic burden with viable muscle

Gives the team pause

Poor distal targetsLimited conduit optionsSevere comorbidity and frailtyA ventricle too damaged to benefitGoals of care that the operation does not serve

The conduits

  • LIMA (internal thoracic artery)

    Harvested from the underside of the chest wall, left attached at its origin.

    The gold-standard graft: an artery that stays open for decades, classically sewn to the LAD.

    One per side and it is precious; injuring it during harvest costs the operation its best conduit.

  • Saphenous vein

    Harvested from the leg, then reversed so its valves do not block flow.

    Long, available and forgiving: the workhorse for the remaining targets.

    A vein living an artery's life: graft disease over years is its known weakness.

  • Radial artery

    The non-dominant forearm, after confirming the ulnar can carry the hand.

    An arterial alternative for high-grade lesions, where competitive flow will not shut it.

    A muscular artery that spasms: it dislikes moderate lesions with competing native flow.

Shared foundations

What the surgeon is thinking

  • Sternotomy and conduit harvest

    Why harvest the conduits before opening the pericardium?

    The operation's clock is the bypass and clamp time, so everything that can happen off the clock does: conduits are prepared while the heart is still working for itself, often two teams at once, chest and leg.

  • Cannulation, bypass, arrest

    Why are we going on bypass at all?

    A beating, blood-filled heart is a moving target with a knife-hostile surface. Bypass hands the circulation to the machine; the cross-clamp and cardioplegia then buy a still, protected field measured in borrowed minutes.

  • The anastomoses

    Why does the LIMA go to the LAD?

    The LAD feeds the largest territory a single vessel owns, and the LIMA is the graft with the longest patency. Marrying the best conduit to the most important target is the single decision with the most future in it.

  • Weaning and closure

    Why is the TEE checked before leaving the OR?

    Weaning is an exam the heart sits under ultrasound: new wall-motion abnormality asks whether a graft is working, and residual air or a struggling ventricle is far cheaper to fix now than in the ICU an hour later.

Decision points

  • Which conduit for a tight proximal LAD lesion?

    • LIMA

      The default marriage: best conduit, most important target.

    • Saphenous vein

      Works, but spends the durable option's advantage on the wrong target.

    • Radial artery

      Reasonable arterial alternative when the LIMA is unavailable.

    Targets are ranked by the muscle they feed, conduits by how long they stay open; the operation pairs them in that order.

  • The heart will not separate from bypass: what categories does the team run?

    • Rhythm

      Pace it, or fix what broke it: potassium, ischaemia, the clamp's cost.

    • Preload

      An empty ventricle cannot eject; filling is the cheapest inotrope.

    • Contractility

      Inotropes, and the question they imply: is a graft down?

    • Afterload

      A vasoplegic circulation after bypass needs a vasoconstrictor, not more volume.

    Weaning failure is approached as physiology, not panic: rhythm, preload, contractility, afterload, and the TEE arbitrating between them. A new regional wall-motion abnormality moves the conversation to the grafts.

Leaving the OR

The handoff

Procedure
CABG x3: LIMA-LAD, SVG-OM1, SVG-PDA
Bypass time
94 min
Cross-clamp
61 min
Events
Weaned on low-dose noradrenaline; TEE satisfactory
Lines & drains
Mediastinal + left pleural drains, atrial and ventricular pacing wires
Watch for
Drain output hourly, rhythm, lactate clearance

A fictional educational patient, handed over the way real ones are.

The postoperative course

  1. ICU arrivalSedated and ventilated; the first hours are drains, pressures and rewarming.
  2. POD 0-1Extubation, pressors weaning, drains slowing; the tachycardic board that still needs reading.
  3. POD 2-3Drains and wires out as criteria allow; the classic window for post-operative AF.
  4. POD 4-6Ward mobilisation, sternal precautions taught, secondary prevention started in earnest.
  5. DischargeHome with a healing sternum and a medication list that is half the operation's long-term benefit.
Continue this patient as a case

Watch it done

  • Cardiopulmonary bypass: the role of the circuit

    Why the operation needs a machine at all: a still, bloodless heart with the body still perfused.

    Source: CTSNet · Watch on YouTube
  • Cardiopulmonary bypass: the circuit

    The path blood takes from the venous cannula through the reservoir, oxygenator and pump back into the aorta.

    Source: CTSNet · Watch on YouTube
  • Cardiopulmonary bypass: circuit components

    Each part of the circuit named and explained: cannulae, reservoir, pump heads, oxygenator, filters and suckers.

    Source: CTSNet · Watch on YouTube
  • Cardiopulmonary bypass: pathophysiology

    What non-pulsatile flow, haemodilution, hypothermia and the foreign circuit do to the body, and why the ICU course follows.

    Source: CTSNet · Watch on YouTube
  • Cardiopulmonary bypass: conduct and weaning

    Going on, running the pump, and the choreography of coming off: rewarming, rhythm, filling and the cannulae out.

    Source: CTSNet · Watch on YouTube
  • Cardiopulmonary bypass: emergency scenarios

    What goes wrong on the pump and what the team does in the first minute: air, dissection at the cannula, pump failure, oxygenator failure.

    Source: CTSNet · Watch on YouTube
  • Coronary artery bypass surgery

    Sternotomy, conduit, bypass and the grafts, in the words of the centre that does the most of them.

    Source: Cleveland Clinic · Watch on YouTube
Find Coronary artery bypass grafting videos on YouTube

What can go wrong

Live this operation as a case →Live this operation as a case →OR Prep this operationReview the instruments